The Definitive Guide to a Calorie Deficit: How Weight Loss Actually Works

True Protein Blog Avatar Fallback reviewed by our Nutrition Team 06 August 2025

Forget the confusing diet fads and conflicting advice, this is your definitive guide to the single, non-negotiable principle that governs all effective and sustainable weight loss.

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The Definitive Guide to a Calorie Deficit: How Weight Loss Actually Works

In the world of health and fitness, you’re bombarded with conflicting advice. Cut carbs, try fasting, eat only at certain times—the list of "quick fixes" for weight loss is endless and confusing. But what if we told you there’s one fundamental principle that underpins all successful, sustainable weight loss? 

There is. It’s called a calorie deficit. 

It’s not a fad, a diet, or a magic pill. It’s the simple science of energy balance, and understanding it is the single most empowering step you can take toward achieving your body composition goals. At True Protein, our goal is to cut through the noise with clear, science-backed guidance. This is your definitive guide to how weight loss actually works. 

 

What Exactly Is a Calorie Deficit? 

A calorie deficit is a state where you expend more energy (calories) than you consume over a period of time. That's it. 

  • Calories In: The energy you get from food and drink. 

  • Calories Out: The energy your body burns to live, breathe, move, and digest food. 

When you consistently consume fewer calories than you burn, your body needs to find that missing energy from somewhere. It finds it by tapping into its stored energy reserves—namely, body fat. This is the physiological process of weight loss. 

This principle is grounded in the First Law of Thermodynamics, which states that energy cannot be created or destroyed. In the context of your body, this means that for fat loss to occur, an energy deficit must exist.

 

How to Calculate Your Calorie Needs & Create a Deficit 

To create a deficit, you first need to know your starting point, or your "maintenance" calories. This is your Total Daily Energy Expenditure (TDEE). Here’s a simple, three-step process to estimate it. 

 

 

Step 1: Calculate Your Basal Metabolic Rate (BMR) 

Your BMR is the number of calories your body burns at rest just to perform its most basic functions, like breathing and cell production. We recommend the Mifflin-St Jeor equation, which is widely considered one of the most accurate formulas. 

  • For Men: BMR = (10 x weight in kg) + (6.25 x height in cm) - (5 x age in years) + 5
  • For Women: BMR = (10 x weight in kg) + (6.25 x height in cm) - (5 x age in years) - 161

Example: A 35-year-old woman who is 165cm tall and weighs 70kg would have a BMR of approximately 1,413 calories. 

 

 

Step 2: Factor in Your Activity Level (TDEE) 

Next, you multiply your BMR by an activity factor to find your TDEE—the total calories you burn in a day, including all your movement. 

Activity Level Multiplier Description
Sedentary BMR x 1.2 Little to no exercise, desk job.
Lightly Active BMR x 1.375 Light exercise / sports 1-3 days/week.
Moderately Active BMR x 1.55 Moderate exercise/sports 3-5 days/week.
Very Active BMR x 1.725 Hard exercise/sports 6-7 days a week.
 Extra Active BMR x 1.9 Very hard exercise, physical job & training.

 

Example: If our 35-year-old woman is moderately active, her TDEE would be 1,413 x 1.55= 2,190 calories. This is her maintenance level.

 

 

Step 3: Determine Your Deficit 

For sustainable fat loss that preserves muscle, a moderate deficit is best. The Australian Government's National Health and Medical Research Council (NHMRC) supports a gradual approach to weight loss for long-term success. 

  • A Healthy Deficit: Aim to subtract 300-500 calories from your TDEE. 

Example: To lose weight, our example woman would aim for an intake of 2,190−400=1,790 calories per day. 

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The Role of Macronutrients: Why Not All Calories Are Created Equal 

While a calorie deficit is the key to weight loss, what you eat fundamentally impacts how you feel, your body composition, and your ability to stick to the plan. This is where macronutrients—protein, carbohydrates, and fats—come in. 

 

Protein: Your Most Important Ally 

When in a calorie deficit, protein is non-negotiable. Here’s why: 

  1. Satiety (Feeling Full): Protein is the most satiating macronutrient, helping you feel fuller for longer and reducing cravings. 

  1. Muscle Preservation: A deficit can cause both fat and muscle loss. A high-protein diet helps protect your hard-earned lean muscle. 

  1. Thermic Effect of Food (TEF): Your body uses more energy to digest protein compared to fats and carbs, slightly boosting your "calories out." 

Hitting your protein goal can be challenging, especially in a deficit. This is where a clean, high-protein, low-calorie option like our True Protein WPI90 or Plant Protein becomes an invaluable tool. It provides a convenient way to boost your protein intake without adding significant extra calories. 

Or if you're time-poor or prefer a complete meal solution, our True Protein Meal Replacement offers a perfectly portioned, nutrient-dense option designed for calorie control and satiety.

Alternatively, if protein powder isn't your thing, our range of Protein Snacks offers a delicious, high-protein replacement for traditional treats, helping you curb cravings and stick to your goals.

 

Carbohydrates: Fuel for Performance 

Carbs have been unfairly villainised. They are your body's preferred energy source, crucial for fuelling workouts and replenishing glycogen stores. Including smart carbohydrates ensures you have the energy to train hard and maintain performance, even on lower calories. 

 

Fats: Essential for Hormones and Health 

Dietary fats are vital for absorbing vitamins and producing key hormones like testosterone. Prioritise healthy, unsaturated fats from sources like avocado, nuts, and olive oil. 

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Common Mistakes to Avoid 

  1. Cutting Calories Too Drastically: A massive deficit can lead to rapid muscle loss, nutrient deficiencies, and a significant drop in metabolic rate, making long-term success much harder. Slow and steady wins the race. 

  1. Ignoring Food Quality: You can lose weight eating junk food in a deficit, but you'll feel terrible. Focus on whole, nutrient-dense foods to support your overall health and energy levels. 

  1. Forgetting About Resistance Training: Cardio is great for burning calories, but resistance training (lifting weights) is what tells your body to keep its muscle. When you feel your energy dip, a clean and effective pre-workout like True PRE or Non Stim PRE can help you maintain workout intensity and get the most out of every session. 

 

Key Takeaways 

  • A calorie deficit is the only requirement for weight loss. It means burning more energy than you consume. 

  • Calculate your maintenance calories (TDEE) by finding your BMR and multiplying it by your activity level. 

  • Aim for a sustainable deficit of 300-500 calories per day for effective fat loss that preserves muscle. 

  • Prioritise a high-protein intake to promote satiety and protect lean muscle mass. Clean protein supplements are an excellent tool for this. 

  • Combine your calorie deficit with resistance training to ensure you are primarily losing fat, not muscle. 

 

References 

Mifflin, M. D., St Jeor, S. T., Hill, L. A., Scott, B. J., Daugherty, S. A., & Koh, Y. O. (1990). A new predictive equation for resting energy expenditure in healthy individuals. The American journal of clinical nutrition, 51(2), 241–247. https://doi.org/10.1093/ajcn/51.2.241 

Paddon-Jones, D., Westman, E., Mattes, R. D., Wolfe, R. R., Astrup, A., & Westerterp-Plantenga, M. (2008). Protein, weight management, and satiety. The American journal of clinical nutrition, 87(5), 1558S–1561S. https://doi.org/10.1093/ajcn/87.5.1558S 

National Health and Medical Research Council (NHMRC). (2013). Australian Dietary Guidelines. Australian Government. https://www.eatforhealth.gov.au/guidelines 

IMPORTANT INFORMATION: all content provided here is of a general nature only and is not a substitute for individualised professional medical advice, diagnosis or treatment and reliance should not be placed on it. For personalised medical or nutrition advice, please make an appointment with your doctor, dietitian or qualified health careprofessional.